Promoter Gene Expression


ADDGENE: PROMOTERS
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A promoter is a region of DNA where transcription of a gene is initiated. Promoters are a vital component of expression vectors because they control the binding of RNA … ...

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16.6: EUKARYOTIC GENE REGULATION - THE PROMOTER AND …
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Oct 31, 2023 Describe the role of promoters in RNA transcription. Genes are organized to make the control of gene expression easier. The promoter region is immediately … ...

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THE CORE PROMOTER: AT THE HEART OF GENE EXPRESSION
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The mechanisms that regulate gene expression comprise diverse multiplayer molecular circuits of multiple dedicated components. The RNA polymerase II (Pol II) core … ...

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EUKARYOTIC CORE PROMOTERS AND THE FUNCTIONAL BASIS OF
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Jun 26, 2018 In this Review, we discuss the defining properties of gene core promoters, including their sequence features, chromatin architecture and transcription initiation … ...

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AI PREDICTS THE EFFECTIVENESS AND EVOLUTION OF GENE …
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Mar 9, 2022 A neural network can predict gene expression from promoter sequence. A long-standing goal of biology is the ability to predict gene expression from DNA sequence. ...

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A UNIVERSAL SYSTEM FOR BOOSTING GENE EXPRESSION IN …
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Mar 16, 2024 12 Altmetric. Metrics. Abstract. We demonstrate a transcriptional regulatory design algorithm that can boost expression in yeast and mammalian cell lines. ...

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THE CORE PROMOTER IS A REGULATORY HUB FOR …
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Sep 10, 2021 In this mini-review, we will highlight the function of the core promoter as the regulatory hub that recruits specific transcription factors to control key developmental … ...

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THE CORE PROMOTER: AT THE HEART OF GENE EXPRESSION
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Aug 1, 2015 1. Introduction. Appropriate temporal and spatial gene expression is a highly complex process underlying the fate and function of different cells and tissues. ...

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PROMOTER - NATIONAL HUMAN GENOME RESEARCH INSTITUTE
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3 days ago A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene. The … ...

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9.3: REGULATION OF GENE EXPRESSION IN EUKARYOTES
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May 15, 2022 The looping of chromosomes that brings enhancers close to promoters (and promoters close to other promoters) seems to be a mechanism to ensure the expression (or inhibition) of groups of … ...

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11: TRANSCRIPTION: PROMOTERS, TERMINATORS AND MRNA
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Jun 20, 2023 Promoters contain binding sites for nuclear proteins, but which of these binding sites have a function in gene expression? This requires a genetic approach for … ...

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PLASMIDS 101: THE PROMOTER REGION – LET'S GO! - ADDGENE
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Apr 3, 2014 Here, we'll cover the promoter, which is necessary for getting the plasmid express our gene of interest. This element is responsible for initiating the transcription of … ...

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PROGRAMMING GENE EXPRESSION WITH COMBINATORIAL PROMOTERS
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Promoters control the expression of genes in response to one or more transcription factors (TFs). The architecture of a promoter is the arrangement and type of binding sites within it. ...

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THE EMERGENCE AND EVOLUTION OF GENE EXPRESSION IN GENOME …
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4 days ago Prokaryotic gene expression requires a stretch of regulatory DNA called a promoter, which contains two promoter motifs called -10 and -35 boxes. ... This ability … ...

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LONG-RANGE ENHANCER–PROMOTER CONTACTS IN GENE EXPRESSION …
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May 13, 2019 One of the paradigm distal regulatory elements is the long-range enhancer that controls the expression of the Shh gene in the developing limb bud. Shh encodes … ...

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PROMOTER SEQUENCE AND ARCHITECTURE DETERMINE EXPRESSION ... - ELIFE
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Nov 15, 2022 Promoter sequence and architecture determine expression variability and confer robustness to genetic variants. Hjörleifur Einarsson. Marco Salvatore. Christian … ...

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PLANT PROMOTERS: THEIR IDENTIFICATION, CHARACTERIZATION, AND ROLE …
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Jun 6, 2023 Two main strategies could be used to study promoter activity. First, gene expression could be analyzed through the detection of mRNA with different techniques, … ...

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PROMOTER SEQUENCE AND ARCHITECTURE DETERMINE EXPRESSION …
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Nov 15, 2022 We show that promoter expression variability reflects the biological process of a gene, demonstrating a selective trade-off between stability for metabolic … ...

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CHAPTER 17. REGULATION OF GENE EXPRESSION – INTRODUCTION TO …
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The process of “turning on” a gene to produce mRNA and protein is called gene expression. Whether in a simple unicellular organism or a complex multi-cellular … ...

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PROMOTER REGULATION AND GENETIC ENGINEERING STRATEGIES FOR …
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Jun 1, 2022 Introduction. Bioconversion of natural polysaccharides such as lignin, cellulose, and hemicellulose to simpler substances has received increased attention due … ...

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GENE EXPRESSION | LEARN SCIENCE AT SCITABLE - NATURE
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Normally, transcription begins when an RNA polymerase binds to a so-called promoter sequence on the DNA molecule. This sequence is almost always located just upstream … ...

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DECIPHERING THE MAIZE GENE ZMGF14–3: IMPLICATIONS FOR PLANT …
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20 hours ago Gene expression analysis suggested that only the expression value of ZmGF14–3 increased with the development of maize, indicating that ZmGF14–3 may … ...

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DELETION OF THE SUGAR IMPORTER GENE - OXFORD ACADEMIC
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Mar 1, 2024 In rice, OsWRKY42 binds to the rice Metallothionein 1d (OsMT1d) promoter and represses its expression to promote senescence (Han et al. 2014). OsWRKY53 … ...

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DOWNSTREAM-OF-GENE (DOG) TRANSCRIPTS CONTRIBUTE TO AN ... - SCIENCE
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3 days ago The gene expression was determined with featureCounts (subread v1.6.1) using GENECODE v43 (primary_assembly) gene annotation with the parameters: “-s 0 … ...

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EFFECTIVE GENE EXPRESSION PREDICTION FROM SEQUENCE BY ... - NATURE
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Oct 4, 2021 Here, we report substantially improved gene expression prediction accuracy from DNA sequences through the use of a deep learning architecture, called Enformer, … ...

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ARABIDOPSIS PROTODERMAL FACTOR2 BINDS ... - NEW PHYTOLOGIST
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5 days ago Gene expression changes in the phospholipid catabolic genes GDPD1 and NPC4 are expected to result in altered phospholipid profiles and abnormal membrane … ...

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EPROMOTERS FUNCTION AS A HUB TO RECRUIT KEY TRANSCRIPTION ... - NATURE
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Nov 18, 2021 Gene expression is controlled by the involvement of gene-proximal (promoters) and distal (enhancers) regulatory elements. Our previous results … ...

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PROFILING EXPRESSION STRATEGIES FOR A TYPE III POLYKETIDE ... - NATURE
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Jun 6, 2024 In terms of promoter choice, while the T7-lac promoter 28 combination is the basis of the most commonly used expression system in E. coli (particularly the pET … ...

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